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Antigenic Specificity | WDFY2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | Protein G purified |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Acts in an adapter protein-like fashion to mediate the interaction between the kinase PRKCZ and its substrate VAMP2 and increases the PRKCZ-dependent phosphorylation of VAMP2 (PubMed:17313651). Positively regulates adipocyte differentiation, by facilitating the phosphorylation and thus inactivation of the anti-adipogenetic transcription factor FOXO1 by the kinase AKT1 (PubMed:18388859). Plays a role in endosomal control of AKT2 signaling; required for insulin-stimulated AKT2 phosphorylation and glucose uptake and insulin-stimulated phosphorylation of AKT2 substrates (By similarity). Participates in transferrin receptor endocytosis (PubMed:16873553). |
Immunogen | Immunogen: Recombinant Human WD repeat and FYVE domain-containing protein 2 protein (2-114AA) |
Other Names | [WD repeat and FYVE domain-containing protein 2; Propeller-FYVE protein1; WDFY2; WDF2; ZFYVE22] |
Gene, Accession # | [WDFY2], Gene ID: 115825, NCBI: NP_443182.1, UniProt: Q96P53 |
Catalog # | MBS7109432 |
Price | $160, $235 |
Order / More Info | WDFY2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |