ATR (Ab-428) Antiobdy Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityATR (Ab-428) Antiobdy
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatepitope affinity purified
Size0.05 mL, 0.1 mL
Concentration1.0 mg/ml
ApplicationsImmunohistochemistry (IHC)
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DescriptionThe antibody detects endogenous level of total ATR protein. ATR encoded by this gene belongs the PI3/PI4-kinase family, and is most closely related to ATM, a protein kinase encoded by the gene mutated in ataxia telangiectasia. This protein and ATM share similarity with Schizosaccharomyces pombe rad3, a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage. This kinase has been shown to phosphorylate checkpoint kinase CHK1, checkpoint proteins RAD17, and RAD9, as well as tumor suppressor protein BRCA1. Mutations of this gene are associated with Seckel syndrome. An alternatively spliced transcript variant of this gene has been reported, however, its full length nature is not known. Transcrip
ImmunogenImmunogen Type: Peptide-KLH Immunogen Description: Peptide sequence around aa.426~430 (G-I-S-P-K) derived from Human ATR.
Other Names[FRP1; MEC1; SCKL; SCKL1]
Gene, Accession #[ATR], Gene ID: 545, NCBI: NP_001175.2, UniProt: Q13535
Catalog #MBS9407994
Price$200, $255
Order / More InfoATR (Ab-428) Antiobdy Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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