Estrogen Receptor Alpha (pSer104) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityEstrogen Receptor Alpha (pSer104)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse (expected from sequence)
Isotypen/a
Formataffinity purified
Size0.05 mL
Concentrationn/a
ApplicationsImmunohistochemistry (IHC) Paraffin, Western Blot (WB)
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DescriptionRabbit anti estrogen receptor alpha (pSer104) antibody recognizes estrogen receptor alpha, also known as ER-alpha, when phosphorylated at serine 104. Estrogen receptor alpha is a member of the nuclear receptor superfamily and also functions as a ligand-regulated transcription factor. Estrogen receptor alpha consists of several domains including the transcription activation function-1 domain (AF-1), the DNA-binding domain, the hinge domain and the ligand-binding domain (AF-2). Estrogen receptor alpha is phosphorylated at serine 104 by MAPKs, Cdk2 and GSK3 (Thomas et al. 2008, Rogatsky et al. 1999, Medunjanin et al. 2005). Phosphorylation at serine 104 contributes to agonist independent activation of estrogen receptor alpha.
ImmunogenImmunogen: Phospho specific-peptide corresponding to residues surrounding serine 104 of human estrogen receptor alpha
Other Names[Estrogen Receptor Alpha (pSer104)], [ESR1; ESR1; ER; ESR; Era; ESRA; ESTRR; NR3A1; ESR; NR3A1; ER]
Gene, Accession #[ESR1], Gene ID: 2099, NCBI: P03372.2, UniProt: P03372
Catalog #MBS225245
Price$375
Order / More InfoEstrogen Receptor Alpha (pSer104) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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