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Antigenic Specificity | SQSTM1/p62 |
Clone | [3F8-E6-G9] |
Host Species | Mouse |
Reactive Species | human, rat |
Isotype | IgG1 |
Format | unconjugated |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Entrez Summary: This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone. [provided by RefSeq, Mar 2009]. UniPort Summary Function: Autophagy receptor that interacts directly with both the cargo to become degraded and an autophagy modifier of the MAP1 LC3 family. Required both for the form |
Immunogen | Immunogen: Purified recombinant fragment of human SQSTM1 (AA: 232-356) expressed in E Coli. Sequence Similarities: Contains 1 ZZ-type zinc finger. |
Other Names | [A170; EBI 3 associated protein of 60 kDa; EBI 3 associated protein p60; EBI3 associated protein of 60 kDa; EBI3 associated protein p60; EBI3-associated protein of 60 kDa; EBIAP; FTDALS3; MGC127197; ORCA; OSF-6; Osi; OSIL; Oxidative stress induced like; p60; p62; p62B; Paget disease of bone 3; PDB 3; PDB3; Phosphotyrosine independent ligand for the Lck SH2 domain of 62 kDa; Phosphotyrosine independent ligand for the Lck SH2 domain p62; Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa; PKC-zeta-interacting protein; Protein kinase C-zeta-interacting protein; Sequestosome 1; Sequestosome-1; SQSTM 1; SQSTM_HUMAN; Sqstm1; STAP; STONE14; Ubiquitin binding protein p62; Ubiquitin-binding protein p62; ZIP 3; ZIP; ZIP3], [SQSTM1; p60; p62; A170; OSIL; PDB3; ZIP3; p62B; NADGP; FTDALS3] |
Gene, Accession # | [SQSTM1/p62], Gene ID: 8878, NCBI: NP_001135770.1, UniProt: Q13501 |
Catalog # | MBS476956 |
Price | $335 |
Order / More Info | SQSTM1/p62 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |