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Antigenic Specificity | TIA-1 |
Clone | [TIA-1] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | unconjugated |
Size | 5 Control Slides, 3 ml (Prediluted), 0.1 mL (Concentrate) |
Concentration | n/a |
Applications | n/a |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | TIA-1 (T-cell intracytoplasmic antigen) is a 15 kDa cytoplasmic granule-associated protein, expressed in lymphocytes processing cytolytic potential. TIA-1 is a member of an RNA-binding protein family and possesses nucleolytic activity against cytotoxic lymphocyte (CTL) target cells. It has been suggested that this protein may be involved in the induction of apoptosis as it preferentially recognizes poly(A) homopolymers and induces DNA fragmentation in CTL targets. The major granule-associated species is a 15 kDa protein thought to be derived from the carboxyl terminus of the 40 kDa product by proteolytic processing. The expression of TIA-1 has been studied in Anaplastic Large Cell Lymphomas (ALCL), NK-cell Lymphomas, Peripheral T-cell Lymph |
Immunogen | n/a |
Other Names | n/a |
Gene, Accession # | [TIA-1] |
Catalog # | MBS370145 |
Price | $130, $195, $210 |
Order / More Info | TIA-1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |