OMI Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityOMI
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formation exchange purified
Size0.1 mL
Concentrationn/a
ApplicationsELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
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DescriptionInhibitor of apoptosis proteins (IAPs) were initially identified in baculoviruses as proteins that inhibit apoptosis of the host cells to allow time for viral replication. Cellular homologues containing at least one baculoviral IAP repeat (BIR) motif essential for their anti-apoptosis activity have been identified in yeasts and higher organisms and often act by binding and inhibiting processed caspases. The activity of these proteins can be modulated by the expression of proteins such as Smac/DIABLO and XAF-1 which displace or prevent the binding of caspases by IAPs. Recently, a mitochondrial serine protease termed Omi/HtrA2 has been found to bind IAPs. Similar to Smac, Omi possesses a conserved IAP-binding motif, but acts to cleave IAPs to
ImmunogenImmunogen Type: Peptide Immunogen Description: Raised against a peptide corresponding to 16 amino acids near the C-terminus of human Omi.
Other Names[HtrA2]
Gene, Accession #[OMI], Gene ID: 27429, NCBI: AAB94569
Catalog #MBS9401189
Price$320
Order / More InfoOMI Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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