LKB1 (Ser428) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | LKB1 (Ser428) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | unconjugated |
| Size | 0.05 mL, 0.2 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This LKB1 (Ser428) antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 408-429 amino acids from the human LKB1. Tumor suppressor serine/threonine-protein kinase that controls the activity of AMP-activated protein kinase (AMPK) family members, thereby playing a role in various processes such as cell metabolism, cell polarity, apoptosis and DNA damage response. Acts by phosphorylating the T-loop of AMPK family proteins, thus promoting their activity: phosphorylates PRKAA1, PRKAA2, BRSK1, BRSK2, MARK1, MARK2, MARK3, MARK4, NUAK1, NUAK2, SIK1, SIK2, SIK3 and SNRK but not MELK. Also phosphorylates non-AMPK family proteins such as STRADA, PTEN and possibly p53/TP53. Acts as a key upstream regulator of AMP |
| Immunogen | n/a |
| Other Names | [Serine/threonine-protein kinase STK11; 2.7.11.1; Liver kinase B1; LKB1; hLKB1; Renal carcinoma antigen NY-REN-19; STK11; LKB1; PJS] |
| Gene, Accession # | [LKB1], Gene ID: 6794, NCBI: NP_000446.1, UniProt: Q15831 |
| Catalog # | MBS9231025 |
| Price | $165, $370 |
| Order / More Info | LKB1 (Ser428) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Jenne D.E.,et al.Nat. Genet. 18:38-43 (1998). Bignell G.R.,et al.Cancer Res. 58:1384-1386 (1998). Ota T.,et al.Nat. Genet. 36:40-45 (2004). Grimwood J.,et al.Nature 428:529-535 (2004). Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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