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Antigenic Specificity | IL1R1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | Protein G purified |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Receptor for IL1A, IL1B and IL1RN. After binding to interleukin-1 associates with the coreceptor IL1RAP to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B, MAPK and other pathways. Signaling involves the recruitment of adapter molecules such as TOLLIP, MYD88, and IRAK1 or IRAK2 via the respective TIR domains of the receptor/coreceptor subunits. Binds ligands with comparable affinity and binding of antagonist IL1RN prevents association with IL1RAP to form a signaling complex. |
Immunogen | Immunogen: Recombinant Human Interleukin-1 receptor type 1 protein (18-320AA) Conjugation: Non-conjugated |
Other Names | [Interleukin-1 receptor type 1; IL-1R-1; IL-1RT-1; IL-1RT1; CD121 antigen-like family member A; Interleukin-1 receptor alpha; IL-1R-alpha; Interleukin-1 receptor type I; p80; CD121a; Interleukin-1 receptor type 1; membrane form; mIL-1R1; mIL-1RI; Interleukin-1 receptor type 1; soluble form; sIL-1R1; sIL-1RI; IL1R1; IL1R; IL1RA; IL1RT1] |
Gene, Accession # | [IL1R1], Gene ID: 3554, NCBI: NP_000868.1, UniProt: P14778 |
Catalog # | MBS7052081 |
Price | $160, $235 |
Order / More Info | IL1R1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |