NTF3 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityNTF3
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatimmunogen affinity purified
Size0.1 mL
Concentration1.0 mg/ml
ApplicationsWestern Blot (WB)
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DescriptionThe antibody detects endogenous level of total NTF3 antibody. NT-3 is a member of the structurally related neurotrophin family of proteins, which includes b-NGF, BDNF and NT-4 (1). NT-3 is expressed in a number of cell types including neuronal cells, eosinophils, and melanocytes (1-3). NT-3 is required for the development of peripheral sensory neurons (4). NT-3 is secreted from cells as a precursor protein, which is proteolytically cleaved into the mature form (1). NT-3 signaling is mediated through two distinct receptors, the neurotrophin receptor p75NTR and the Trk tyrosine kinase receptor TrkC. While all neurotrophins bind to the p75NTR receptor, NT-3 preferentially binds to TrkC and, with lesser affinity, TrkB (1).
ImmunogenImmunogen Type: Recombinant Protein Immunogen Description: Recombinant protein of human NTF3.
Other Names[NTF3; HDNF; MGC129711; NGF-2; NGF2; NT3]
Gene, Accession #[NTF3], Gene ID: 4908, NCBI: NP_001096124.1, UniProt: P20783
Catalog #MBS9402409
Price$255
Order / More InfoNTF3 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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