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Antigenic Specificity | DISC1 (C-term), 701-728 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.39 |
Applications | ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This DISC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 701-728 amino acids from the C-terminal region of human DISC1. This gene encodes a protein with multiple coiled coilmotifs which is located in the nucleus, cytoplasm and mitochondria.The protein is involved in neurite outgrowth and corticaldevelopment through its interaction with other proteins. This geneis disrupted in a t(1;11)(q42.1;q14.3) translocation whichsegregates with schizophrenia and related psychiatric disorders ina large Scottish family. Alternate transcriptional splice variants,encoding different isoforms, have been characterized. [provided byRefSeq]. |
Immunogen | n/a |
Other Names | [Disrupted in schizophrenia 1 protein; DISC1; KIAA0457] |
Gene, Accession # | [DISC1], Gene ID: 27185, NCBI: NP_001012975.1, UniProt: Q9NRI5 |
Catalog # | MBS9202075 |
Price | $165, $370 |
Order / More Info | DISC1 (C-term), 701-728 Antibody from MYBIOSOURCE INC. |
Product Specific References | Park, Y.U., et al. Proc. Natl. Acad. Sci. U.S.A. 107(41):17785-17790(2010) Raznahan, A., et al. Mol. Psychiatry (2010) In press : Ruano, G., et al. Pharmacogenomics 11(7):959-971(2010) Kaibuchi, K., et al. Nihon Shinkei Seishin Yakurigaku Zasshi 30(3):149-152(2010) Shulman, J.M., et al. PLoS ONE 5 (6), E11244 (2010) : |