Phospho-MAP2K1/MAP2K2-S217/S221 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Phospho-MAP2K1/MAP2K2-S217/S221 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.05 mL, 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3. The activation of this kinase itself is dependent on the Ser/Thr phosphorylation by MAP kinase kinase kinases. Mutations in this gene cause cardiofaciocutaneous syndrome (CFC syndrome), a disease characterized by heart defects, mental retardation, and distinctive facial features similar to those found in Noonan syndrome. The inhibition or degradation of this kinase is also found to be involved in the pathogenesis of Yersinia and anthrax. A pseudogene, which is located on chr |
| Immunogen | Immunogen: A phospho specific peptide corresponding to residues surrounding serine 217/221 of human MAP2K1/MAP2K2. Calculated Molecular Weight: 45kDa |
| Other Names | [Phospho-MAP2K1/MAP2K2-S217/S221: CFC3/CFC4; MEK1/MEK2; MKK1/MKK2; MAPKK1/MAPKK2; PRKMK1/PRKMK2], [MAP2K1; MAP2K1; CFC3; MEK1; MKK1; MAPKK1; PRKMK1; MEK1; PRKMK1; MAP kinase kinase 1; MAPKK 1; MKK1; MEK 1] |
| Gene, Accession # | [MAP2K1/MAP2K2], Gene ID: 5604, NCBI: Q02750.2, UniProt: Q02750 |
| Catalog # | MBS128486 |
| Price | $235, $350, $525 |
| Order / More Info | Phospho-MAP2K1/MAP2K2-S217/S221 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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