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Antigenic Specificity | SERPINB6 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: SERPINB6 antibody detects endogenous levels of total SERPINB6. Function: May be involved in the regulation of serine proteinases present in the brain or extravasated from the blood (By similarity). Inhibitor of cathepsin G, kallikrein-8 and thrombin. May play an important role in the inner ear in the protection against leakage of lysosomal content during stress and loss of this protection results in cell death and sensorineural hearing loss.Subunit Structure: Forms a complex with the monomeric form of beta-tryptase.Similarity: Belongs to the serpin family. Ov-serpin subfamily. |
Immunogen | Immunogen: A synthesized peptide derived from human SERPINB6 Subcellular Location: Cytoplasm. Tissue Specificity: Expressed in keratinocytes (at protein level). Highest levels in skeletal muscle. Also found in placenta, cardiac muscle, lung, liver, kidney and pancreas. Expressed in the inner ear hair cells. Expressed abundantly by normal mast cells in different tissues and by mast cells in mastocytoma lesions. |
Other Names | [CAP; Cytoplasmic antiproteinase; Peptidase inhibitor 6; PI-6; PI6; Placental thrombin inhibitor; Protease inhibitor 6 (placental thrombin inhibitor); PTI; Serpin B6; SERPINB6; SPB6_HUMAN] |
Gene, Accession # | [SERPINB6], Gene ID: 5269, NCBI: NP_001182220.2, UniProt: P35237 |
Catalog # | MBS9610211 |
Price | $240, $280 |
Order / More Info | SERPINB6 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |