Edit |   |
Antigenic Specificity | E-selectin, Human |
Clone | ENA1 |
Host Species | Mouse |
Reactive Species | reactivity: human. cross reactivity: baboon, chimpanzee, cynomolgus monkey, rhesus monkey |
Isotype | IgG1 |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | F, FS, Immunoassay (IA), Immunoprecipitation (IP) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Product Description: ENA1 reacts with E-selectin CD62-E, previous designated the Endothelial Leucocyte Adhesion Molecule-1 (ELAM-1). The antibody reacts with human endothelial cells activated with TNF-alpha, IL-1 or endotoxin. The antibody was found to react also with cells transfected with the E-selectin gene. The antibody inhibits the adhesion of granulocytes both neutrophilic and eosinophilic. |
Immunogen | n/a |
Other Names | [E-selectin; E-selectin; E-selectin; ELAM-1; endothelial adhesion molecule 1; CD62 antigen-like family member E; endothelial leukocyte adhesion molecule 1; leukocyte endothelial cell adhesion molecule 2; leukocyte-endothelial cell adhesion molecule 2; selectin E; CD62 antigen-like family member E; Endothelial leukocyte adhesion molecule 1; ELAM-1; Leukocyte-endothelial cell adhesion molecule 2; LECAM2; CD_antigen: CD62E], [SELE; SELE; ELAM; ESEL; CD62E; ELAM1; LECAM2; ELAM1; ELAM-1; LECAM2] |
Gene, Accession # | Gene ID: 6401, NCBI: NP_000441.2 |
Catalog # | MBS584179 |
Price | $520 |
Order / More Info | E-selectin, Human Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Leeuwenberg, JFM et al; Induction of an activation antigen on human endothelial cells in vitro. Eur J Immunol 1989, 19: 715 2. Leeuwenberg, JFM et al; Adhesion of polymorphonuclear cells to human endothelial cells. Adhesionmolecule dependent, and Fc-receptor-mediated adhesion-molecule-independent mechanisms. Clin and Exp Immunol 1990, 81: 496 3. Leeuwenberg, JFM et al; Functional polymorphism of IgG FcRII (CD32) on human neutrophils. Immunology 1990, 71: 301 4. Leeuwenberg, JFM et al; Interferon-gamma regulates the expression of an adhesion molecule ELAM-1 and IL-6 production by human endothelial cells in vitro. J Immunology 1990, 145: 2110 |