AURKB Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityAURKB
Clone[13E8D3]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1
Formatascites
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FC/FACS), ELISA (EIA)
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DescriptionAURKB (aurora kinase B, AIK2 or aurora-B), with 344-amino acid protein(about 39kDa), localizes to microtubules near kinetochores, specifically to the specialized microtubules called K-fibers. AURKB is a mitotic protein kinase, which phosphorylates histone H3 and regulates Chromosomal segregation during mitosis and meiosis.It may regulates several stages of mitosis such as centrosome separation, chromosome segregation and cytokinesis. Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. ARK-2
ImmunogenImmunogen: Purified recombinant fragment of AURKB expressed in E. Coli.
Other Names[aurora kinase B isoform 1; Aurora kinase B; aurora kinase B; aurora kinase B; Aurora 1; Aurora- and IPL1-like midbody-associated protein 1; AIM-1; Aurora/IPL1-related kinase 2; ARK-2; Aurora-related kinase 2; STK-1; Serine/threonine-protein kinase 12; Serine/threonine-protein kinase 5; Serine/threonine-protein kinase aurora-B]
Gene, Accession #[AURKB], Gene ID: 9212, NCBI: NP_004208.2, UniProt: Q96GD4
Catalog #MBS8538338
Price$280
Order / More InfoAURKB Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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