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Antigenic Specificity | GCG (N-term), 25-54 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 2 |
Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This GCG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 25-54 amino acids from the N-terminal region of human GCG. GCG is actually a preproprotein that is cleaved into four distinct mature peptides. One of these, glucagon, is a pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. Glucagon is a ligand for a specific G-protein linked receptor whose signalling pathway controls cell proliferation. Two of the other peptides are secreted from gut endocrine cells and promote nutrient absorption through distinct mechanisms. Finally, the fourth peptide is similar to glicentin, an active enteroglucagon. |
Immunogen | n/a |
Other Names | [Glucagon; Glicentin; Glicentin-related polypeptide; GRPP; Oxyntomodulin; OXM; OXY; Glucagon; Glucagon-like peptide 1; GLP-1; Incretin hormone; Glucagon-like peptide 1(7-37); GLP-1(7-37); Glucagon-like peptide 1(7-36); GLP-1(7-36); Glucagon-like peptide 2; GLP-2; GCG] |
Gene, Accession # | [GCG], Gene ID: 2641, NCBI: NP_002045.1, UniProt: P01275 |
Catalog # | MBS9201502 |
Price | $165, $370 |
Order / More Info | GCG (N-term), 25-54 Antibody from MYBIOSOURCE INC. |
Product Specific References | Jacobo,S.M., J. Pharmacol. Exp. Ther. 330 (1), 283-293 (2009) Root-Bernstein,R.J. Mol. Recognit. 22 (3), 177-187 (2009) |