FAIM Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityFAIM
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionSpecificity: FAIM antibody detects endogenous levels of total FAIM. Description: FAIM (Fas apoptosis inhibitory molecule) was identified as a protein that was inducibly expressed in B lymphocytes resistant to Fas-mediated apoptosis (1). Expression of FAIM inhibits receptor-mediated apoptosis in B cells as well as other cell types (1-3). FAIM is expressed in germinal center B cells, is positively regulated by IRF-4, and is also capable of inducing IRF-4 expression in a feed-forward mechanism (4). FAIM also regulates T cell receptor-mediated apoptosis by modulating Akt activation and Nur77 expression (2). Knockout mice for FAIM show an increased sensitivity to Fas-mediated apoptosis within B and T cells as well as hepatocytes (5). An alternat
ImmunogenImmunogen: A synthesized peptide derived from human FAIM Subcellular Location: Cytoplasm.
Other Names[FAIM 1; Faim; FAIM1; FAIM1_HUMAN; Fas apoptotic inhibitory molecule 1; Fas apoptotic inhibitory molecule]
Gene, Accession #[FAIM], Gene ID: 55179, NCBI: NP_001028202.1, UniProt: Q9NVQ4
Catalog #MBS9606779
Price$240, $280
Order / More InfoFAIM Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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