NIK Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | NIK |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat, dog, hamster |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.03 mg, 0.1 mg |
| Concentration | 0.5 mg/ml |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Background: NIK (NF-kB-inducing kinase) is a member of the MAP kinase kinase kinase family that binds TRAF2 and stimulates NF-kB activity. NIK was initially isolated from a human B cell cDNA library and contains 795 amino acids with an apparent molecular weight of slightly more than 97 kDa on SDS gel. NIK is a serine/threonine kinase and its kinase activity contributes to IkB phosphorylation. The carboxyl terminal segment of NIK binds TRAF2. A mutant NIK with intact carboxyl terminus but without the two lysine residues at its catalytic domain serves as a dominant-negative inhibitor for NF-kB activation. NIK also interacts with TRAF6 and mediates IL-1-induced NF-kB activation. |
| Immunogen | Immunogen: Synthetic peptide surrounding amino acid 927of human NIK |
| Other Names | [MAP3K14; hsNIK; FTDCR1B; HSNIK; EC 2.7.11.25], [MAP3K14; MAP3K14; HS; NIK; HSNIK; FTDCR1B; NIK; HsNIK] |
| Gene, Accession # | [NIK], Gene ID: 9020, NCBI: NP_003945.2, UniProt: Q99558 |
| Catalog # | MBS840977 |
| Price | $150, $300 |
| Order / More Info | NIK Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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