Edit |   |
---|---|
Antigenic Specificity | ST5 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total ST5 protein. Guanine nucleotide exchange factor (GEF) which may activate RAB9A and RAB9B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. May be involved in cytoskeletal organization and tumorogenicity. Isoform 1 seems to be involved in a signaling transduction pathway leading to activation of MAPK1/ERK2. Isoform 3 may block ERK2 activation stimulated by ABL1. Isoform 3 may alter cell morphology and cell growth.Lichy J.H., Nucleic Acids Res. 24:4700-4708(1996).Amid C., Cytogenet. Cell Genet. 93:284-290(2001).Lichy J.H., Cell Growth Differ. 3:541-548(1992). |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized peptide derived from internal of human ST5. |
Other Names | [Suppression of tumorigenicity 5; HeLa tumor suppression 1; DENN domain-containing protein 2B; ST5; DENND2B] |
Gene, Accession # | [ST5], Gene ID: 6764, NCBI: NP_005409.3, UniProt: P78524 |
Catalog # | MBS9411591 |
Price | $200, $255 |
Order / More Info | ST5 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |