Edit |   |
---|---|
Antigenic Specificity | PD-L1 (CD274) |
Clone | monoclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.03 mg, 0.1 mg, 0.1 mg |
Concentration | n/a |
Applications | Immunohistochemistry (IHC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Involved in the costimulatory signal, essential for T- cell proliferation and production of IL10 and IFNG, in an IL2- dependent and a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation and cytokine production. |
Immunogen | Immunogen: A synthesized peptide derived from human PD-L1 (CD274). Subcellular Localization: Isoform 1: Cell membrane; Single-pass type I membrane protein. Tissue Specificity: Highly expressed in the heart, skeletal muscle, placenta and lung. Weakly expressed in the thymus, spleen, kidney and liver. Expressed on activated T- and B-cells, dendritic cells, keratinocytes and monocytes. |
Other Names | [Programmed cell death 1 ligand 1; PD-L1; PDCD1 ligand 1; Programmed death ligand 1; B7 homolog 1; B7-H1; CD274; CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1], [CD274] |
Gene, Accession # | [PD-L1], Gene ID: 29126, NCBI: NP_001254635.1, UniProt: Q9NZQ7 |
Catalog # | MBS179113 |
Price | $160, $340, $340 |
Order / More Info | PD-L1 (CD274) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |