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Antigenic Specificity | ITPR1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | Protein G purified |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Intracellular channel that mediates calcium release from the endoplasmic reticulum following stimulation by inositol 1, 4, 5-trisphosphate (PubMed:27108797). Involved in the regulation of epithelial secretion of electrolytes and fluid through the interaction with AHCYL1 (By similarity). Plays a role in ER stress-induced apoptosis. Cytoplasmic calcium released from the ER triggers apoptosis by the activation of CaM kinase II, eventually leading to the activation of downstream apoptosis pathways (By similarity). |
Immunogen | Immunogen: Recombinant Human Inositol 1, 4, 5-trisphosphate receptor type 1 protein (1707-1966AA) |
Other Names | [Inositol 1; 4; 5-trisphosphate receptor type 1; IP3 receptor isoform 1; IP3R 1; InsP3R1; Type 1 inositol 1; 4; 5-trisphosphate receptor; Type 1 InsP3 receptor; ITPR1; INSP3R1] |
Gene, Accession # | [ITPR1], Gene ID: 3708, NCBI: NP_001093422.2, UniProt: Q14643 |
Catalog # | MBS7105209 |
Price | $160, $235 |
Order / More Info | ITPR1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |