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Antigenic Specificity | MAGG1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: MAGG1 antibody detects endogenous levels of total MAGG1. Function: Component of the SMC5-SMC6 complex, a complex involved in repair of DNA double-strand breaks by homologous recombination (PubMed:20864041, PubMed:27427983). The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination in ALT (alternative lengthening of telomeres) cell lines and mediates sumoylation of shelterin complex (telosome) components which is proposed to lead to shelterin complex disassembly in ALT-associated PML bodies (APBs). In vitro enhances ubiquitin ligase activity of NSMCE1. Proposed to act through recruitment |
Immunogen | Immunogen: A synthesized peptide derived from human MAGG1 Subcellular Location: Cytoplasmic and Nuclear Tissue Specificity: Ubiquitous. Predicted Cross Reactivity: Bovine, Horse, Rabbit Similarity: Bovine (91%), Horse (91%), Rabbit (82%) |
Other Names | [HCA4; hepatocellular carcinoma-associated protein 4; hepatocellular carcinoma-associated protein HCA4; MAGE-G1 antigen; MAGEG1; MAGEL3; melanoma antigen, family G, 1; melanoma-associated antigen G1; necdin-like 2; necdin-like gene 2; necdin-like protein 2; NSE3; NSMCE3] |
Gene, Accession # | [MAGG1], Gene ID: 56160, NCBI: NP_619649.1, UniProt: Q96MG7 |
Catalog # | MBS9602901 |
Price | $240, $280 |
Order / More Info | MAGG1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |