Human Double-strand break repair protein MRE11A Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Human Double-strand break repair protein MRE11A |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | antigen affinity purified |
| Size | 0.05 mL, 0.1 mL |
| Concentration | n/a |
| Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Component of the MRN complex, which plays a central role in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity and meiosis. The complex possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity, which are provided by MRE11A. RAD50 may be required to bind DNA ends and hold them in close proximity. This could facilitate searches for short or long regions of sequence homology in the recombining DNA templates, and may also stimulate the activity of DNA ligases and/or restrict the nuclease activity of MRE11A to prevent nucleolytic degradation past a given point. The complex may also be required for DNA damage signaling via activation of the ATM kinase. In telomeres the |
| Immunogen | Immunogen: Recombinant human Double-strand break repair protein MRE11A protein(1-205aa) Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-5859 / sc-5858 / sc-22767 |
| Other Names | [Meiotic recombination 11 homolog 1; MRE11 homolog 1; Meiotic recombination 11 homolog A; MRE11 homolog A; MRE11A; HNGS1; MRE11], [MRE11A; MRE11A; ATLD; HNGS1; MRE11; MRE11B; HNGS1; MRE11; MRE11 homolog 1; MRE11 homolog A] |
| Gene, Accession # | [MRE11A], Gene ID: 4361, NCBI: NP_005581.2, UniProt: P49959 |
| Catalog # | MBS1493565 |
| Price | $120, $160 |
| Order / More Info | Human Double-strand break repair protein MRE11A Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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