HUWE1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHUWE1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatantigen affinity purified
Size0.1 mL
Concentration1mg/ml
ApplicationsImmunohistochemistry (IHC)
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DescriptionThe antibody detects endogenous levels of total HUWE1 protein. This gene encodes a protein containing a C-terminal HECT (E6AP type E3 ubiquitin protein ligase) domain that functions as an E3 ubiquitin ligase. The encoded protein is required for the ubiquitination and subsequent degradation of the anti-apoptotic protein Mcl1 (myeloid cell leukemia sequence 1 (BCL2-related)). This protein also ubiquitinates the p53 tumor suppressor, core histones, and DNA polymerase beta. Mutations in this gene are associated with Turner type X-linked syndromic mental retardation.
ImmunogenImmunogen: Synthetic peptide of human HUWE1 Immunogen Type: Peptide
Other Names[MULE; Ib772; LASU1; UREB1; HECTH9; URE-B1; ARF-BP1; HSPC272]
Gene, Accession #[HUWE1], Gene ID: 10075, NCBI: NP_113584.3, UniProt: Q7Z6Z7
Catalog #MBS9417380
Price$255
Order / More InfoHUWE1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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