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Antigenic Specificity | Apbb1 - N-terminal region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | cow, dog, guinea pig, horse, human, mouse, rabbit, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This is a rabbit polyclonal antibody against Apbb1. It was validated on Western BlotTarget Description: Apbb1 is an adapter protein that forms a transcriptionally active complex with the gamma-secretase-derived amyloid precursor protein (APP) intracellular domain.Apbb1 plays a central role in the response to DNA damage by translocating to the nucleus and inducing apoptosis. Apbb1 may act by specifically recognizing and binding histone H2AX phosphorylated on 'Tyr-142' (H2AXY142ph) at double-strand breaks (DSBs), recruiting other pro-apoptosis factors such as MAPK8/JNK1. Apbb1 is required for histone H4 acetylation at double-strand breaks (DSBs). Its ability to specifically bind modified histones and chromatin modifying enzymes such a |
Immunogen | Immunogen: The immunogen is a synthetic peptide corresponding to a region of Mouse |
Other Names | [amyloid-beta A4 protein-binding family B member 1 isoform 2; Amyloid beta A4 precursor protein-binding family B member 1; amyloid-beta A4 precursor protein-binding family B member 1; amyloid beta A4 precursor protein-binding family B member 1; amyloid beta (A4) precursor protein-binding, family B, member 1; Protein Fe65] |
Gene, Accession # | [APBB1], Gene ID: 11785, NCBI: NP_033815, UniProt: Q9QXJ1 |
Catalog # | MBS3212241 |
Price | $335 |
Order / More Info | Apbb1 - N-terminal region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |