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Antigenic Specificity | TBP |
Clone | [830CT4.3.3] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | ascites |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Purified His-tagged TBP protein was used to produced this monoclonal antibody. General transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID. Binding of TFIID to the TATA box is the initial transcriptional step of the pre-initiation complex (PIC), playing a role in the activation of eukaryotic genes transcribed by RNA polymerase II. Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (preinitiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1 with the rDNA promoter. SL1 is involved in stabilization of nucleolar transcription factor 1/UB |
Immunogen | n/a |
Other Names | [TATA-box-binding protein; TATA sequence-binding protein; TATA-binding factor; TATA-box factor; Transcription initiation factor TFIID TBP subunit; TBP; GTF2D1; TF2D; TFIID] |
Gene, Accession # | [TBP], Gene ID: 6908, NCBI: NP_001165556.1, UniProt: P20226 |
Catalog # | MBS9200148 |
Price | $370 |
Order / More Info | TBP Antibody from MYBIOSOURCE INC. |
Product Specific References | Hoffmann A., et al. Nature 346:387-390(1990). Peterson M.G., et al. Science 248:1625-1630(1990). Kao C.C., et al. Science 248:1646-1650(1990). Ebert L., et al. Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases. Mungall A.J., et al. Nature 425:805-811(2003). |