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Antigenic Specificity | CIRP/CIRBP |
Clone | [1C9] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2a, k |
Format | Protein A purified |
Size | 0.05 mg |
Concentration | n/a |
Applications | ELISA (EIA), Immunofluorescence (IF), Immunohistochemistry (IHC) Paraffin, Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Human CIRP/CIRBP. Cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involvedin cell survival. Acts as a translational activator. Seems to play anessential role in cold-induced suppression of cell proliferation. Binds specifically to the 3'-untranslated regions (3'-UTRs) ofstress-responsive transcripts RPA2 and TXN. Acts as a translationalrepressor By similarity. Promotes assembly of stress granules (SGs), when overexpressed. |
Immunogen | Immunogen: CIRBP (NP 001271.1, aa1-90 partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Conjugation: Unconjugated |
Other Names | [Goat to Human CIRP/CIRBP; CIRBP; A18 hnRNP; A18HNRNP; CIRP] |
Gene, Accession # | [CIRP/CIRBP], Gene ID: 1153, NCBI: NP_001271.1, UniProt: Q14011 |
Catalog # | MBS2400966 |
Price | $605 |
Order / More Info | CIRP/CIRBP Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |