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Antigenic Specificity | MAPK15 (N-term), 32-61 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 2 |
Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This MAPK15 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 32-61 amino acids from the N-terminal region of human MAPK15. The ERKs are a subfamily of the MAPKs that have been implicated in cell growth and differentiation. Extracellular signal-regulated kinase 8 (Erk8) is a large MAP kinase whose activity is controlled by serum and the c-Src non-receptor tyrosine kinase. ERK8 down-regulates transactivation of the glucocorticoid receptor through Hic-5 and can negatively regulate transcriptional co-activation of androgen receptor and GRalpha by Hic-5 in a kinase-independent manner, suggesting a broader role for ERK8 in the regulation of nuclear receptors beyond estrogen receptor alpha. Erk8 is a nov |
Immunogen | n/a |
Other Names | [Mitogen-activated protein kinase 15; MAP kinase 15; MAPK 15; Extracellular signal-regulated kinase 7; ERK-7; Extracellular signal-regulated kinase 8; ERK-8; MAPK15; ERK7; ERK8] |
Gene, Accession # | [MAPK15], Gene ID: 225689, NCBI: NP_620590.2, UniProt: Q8TD08 |
Catalog # | MBS9207755 |
Price | $165, $370 |
Order / More Info | MAPK15 (N-term), 32-61 Antibody from MYBIOSOURCE INC. |
Product Specific References | Saelzler,M.P., J. Biol. Chem. 281 (24), 16821-16832 (2006) Iavarone,C., J. Biol. Chem. 281 (15), 10567-10576 (2006) Klevernic,I.V., Biochem. J. 394 (PT 1), 365-373 (2006) Suzuki,Y., Genome Res. 14 (9), 1711-1718 (2004) |