MARCH1 (Internal) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityMARCH1 (Internal)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshumanpredicted: mouse
Isotypen/a
Formatimmunoaffinity purified
Size0.05 mL
Concentrationn/a
ApplicationsImmunohistochemistry (IHC) Paraffin, Western Blot (WB)
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DescriptionRecognizes endogenous levels of 42064 protein. E3 ubiquitin-protein ligase that mediates ubiquitination of TFRC, CD86, FAS and MHC class II proteins, such as HLA-DR alpha and beta, and promotes their subsequent endocytosis and sorting to lysosomes viamultivesicular bodies. By constitutively ubiquitinating MHC class IIproteins in immature dendritic cells, down-regulates their cell surfacelocalization thus sequestering them in the intracellular endosomalsystem.
ImmunogenImmunogen: KLH-conjugated synthetic peptide encompassing a sequence within the central region of human 42064. Conjugation: Unconjugated
Other Names[Rabbit (IgG) to Human MARCH1; MARCH1; MARCH-I; RING finger protein 171; RNF171]
Gene, Accession #[MARCH1], Gene ID: 55016, NCBI: NP_060393.1, UniProt: Q8TCQ1
Catalog #MBS2401774
Price$530
Order / More InfoMARCH1 (Internal) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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