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Antigenic Specificity | PUMA / bbc3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 0.5 mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Background: PUMA (p53 upregulated modulator of apoptosis) is one of the pro-apoptotic Bcl-2 family members which are also transcriptional targets of p53. PUMA gene encodes two BH3 domain-containing proteins termed PUMA-alpha and PUMA-beta. PUMA proteins bind Bcl-2, localize to the mitochondria, and induce cytochrome c release and apoptosis in response to p53. PUMA may be a direct mediator of p53-induced apoptosis. |
Immunogen | Immunogen: Synthetic peptide mapping to the C-terminus of human PUMA. |
Other Names | [JFY1; PUMA; FLJ42994; BBC3], [BBC3; BBC3; JFY1; PUMA; JFY-1; PUMA] |
Gene, Accession # | [PUMA/bbc3], Gene ID: 27113, NCBI: NP_001120712.1, UniProt: Q9BXH1 |
Catalog # | MBS841442 |
Price | $305 |
Order / More Info | PUMA / bbc3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |