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Antigenic Specificity | Human OSTEOPONTIN (C-TERMINAL) |
Clone | polyclonal |
Host Species | Goat |
Reactive Species | dog (expected from sequence), mouse (expected from sequence), rat (expected from sequence). Antibody reactivity and working conditions may vary between species. |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | IgG concentration 0.5mg/ml |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This item recognises an epitope within the C-terminal (CT) region of osteopontin, an acid-rich, multidomain, phosphorylated 60kD glycoprotein. Osteopontin is a secreted chemokine-like protein that is a member of the SIBLING family, and is synthesised by many cell types. . . Osteopontin is involved in enhancing production of interferon-gamma and interleukin-12 and reducing production of interleukin-10. It is essential in the pathway that leads to type I immunity. Osteoponitn is also thought to be important to cell-matrix interaction, and can bind fibronectin, collagen and calcium. . . Osteopontin has been suggested to have a role in atherosclerosis, bone remodelling, angiogenesis, wound healing and tissue injuries. MBS221360 recognises a |
Immunogen | Immunogen: Peptide with sequence C-DPKSKEEDKHLK, from the C-terminal of osteopontin. Buffer Solution: TRIS buffered saline Antiserum Preparation: Antisera to osteopontin (CT) were raised by repeated immunisations of goat with highly purified antigen. Purified IgG prepared by affinity chromatography. Target Species: Human |
Other Names | [osteopontin isoform OPN-b; Osteopontin; osteopontin; SPP1/CALPHA1 fusion; early T-lymphocyte activation 1; nephropontin; osteopontin/immunoglobulin alpha 1 heavy chain constant region fusion protein; secreted phosphoprotein 1 (osteopontin, bone sialoprotein I, early T-lymphocyte activation 1); urinary stone protein; uropontin; secreted phosphoprotein 1; Bone sialoprotein 1; Nephropontin; Secreted phosphoprotein 1; SPP-1; Urinary stone protein; Uropontin], [SPP1; SPP1; OPN; BNSP; BSPI; ETA-1; BNSP; OPN; SPP-1] |
Gene, Accession # | Gene ID: 6696, NCBI: NP_000573.1, UniProt: P10451 |
Catalog # | MBS221360 |
Price | $550 |
Order / More Info | Human OSTEOPONTIN (C-TERMINAL) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |