Bax (active monomer) [6A7] Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityBax (active monomer) [6A7]
Clone[6A7]
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
IsotypeIgG, kappa
FormatProtein A purified
Size0.2 mg
Concentration1 mg/ml
ApplicationsImmunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB)
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DescriptionSpecificity: In the presence of nonionic detergent, the antibody avidly binds the monomeric form of Bax, but not Bax complexed with either Bcl-XL or Bcl-2. [6A7 ] Bax antibody only recognizes conformationally changed active Bax. Recombinant monoclonal antibody to Bax (active monomer). Manufactured using a proprietary Recombinant Platform with variable regions (i.e. specificity) from the hybridoma 6A7. KLH conjugated to peptides corresponding to amino acids 3-16 of murine Bax (CGSGEQLGSGGPTSS), amino acids 3-16 of human Bax (CGSGEQPRGGGPTSS), and amino acids 12-24 shared by Bax from both species (CGPTSSEQIMKTGA).
ImmunogenImmunogen: KLH conjugated to peptides corresponding to amino acids 3-16 of murine Bax (CGSGEQLGSGGPTSS), amino acids 3-16 of human Bax (CGSGEQPRGGGPTSS), and amino acids 12-24 shared by Bax from both species (CGPTSSEQIMKTGA).
Other Names[Apoptosis regulator BAX; Bcl-2-like protein 4; Bcl2-L-4], [BAX; BAX; BCL2L4; BCL2L4; Bcl2-L-4]
Gene, Accession #[BAX], Gene ID: 581, NCBI: NP_001278357.1, UniProt: Q07812
Catalog #MBS488281
Price$425
Order / More InfoBax (active monomer) [6A7] Antibody from MYBIOSOURCE INC.
Product Specific ReferencesHsu YT, Youle RJ. Nonionic detergents induce dimerization among members of the Bcl-2 family. J Biol Chem. 1997 May 23; 272(21):13829-34. PMID:9153240
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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