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Antigenic Specificity | Bax (active monomer) [6A7] |
Clone | [6A7] |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | IgG, kappa |
Format | Protein A purified |
Size | 0.2 mg |
Concentration | 1 mg/ml |
Applications | Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: In the presence of nonionic detergent, the antibody avidly binds the monomeric form of Bax, but not Bax complexed with either Bcl-XL or Bcl-2. [6A7 ] Bax antibody only recognizes conformationally changed active Bax. Recombinant monoclonal antibody to Bax (active monomer). Manufactured using a proprietary Recombinant Platform with variable regions (i.e. specificity) from the hybridoma 6A7. KLH conjugated to peptides corresponding to amino acids 3-16 of murine Bax (CGSGEQLGSGGPTSS), amino acids 3-16 of human Bax (CGSGEQPRGGGPTSS), and amino acids 12-24 shared by Bax from both species (CGPTSSEQIMKTGA). |
Immunogen | Immunogen: KLH conjugated to peptides corresponding to amino acids 3-16 of murine Bax (CGSGEQLGSGGPTSS), amino acids 3-16 of human Bax (CGSGEQPRGGGPTSS), and amino acids 12-24 shared by Bax from both species (CGPTSSEQIMKTGA). |
Other Names | [Apoptosis regulator BAX; Bcl-2-like protein 4; Bcl2-L-4], [BAX; BAX; BCL2L4; BCL2L4; Bcl2-L-4] |
Gene, Accession # | [BAX], Gene ID: 581, NCBI: NP_001278357.1, UniProt: Q07812 |
Catalog # | MBS488281 |
Price | $425 |
Order / More Info | Bax (active monomer) [6A7] Antibody from MYBIOSOURCE INC. |
Product Specific References | Hsu YT, Youle RJ. Nonionic detergents induce dimerization among members of the Bcl-2 family. J Biol Chem. 1997 May 23; 272(21):13829-34. PMID:9153240 |