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Antigenic Specificity | NFAT1 |
Clone | monoclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.03 mg, 0.1 mg, 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Plays a role in the inducible expression of cytokine genes in T-cells, especially in the induction of the IL-2, IL-3, IL-4, TNF-alpha or GM-CSF. Promotes invasive migration through the activation of GPC6 expression and WNT5A signaling pathway. |
Immunogen | Immunogen: A synthesized peptide derived from human NFAT1. Subcellular Localization: Cytoplasm. Nucleus. Cytoplasmic for the phosphorylated form and nuclear after activation that is controlled by calcineurin-mediated dephosphorylation. Rapid nuclear exit of NFATC is thought to be one mechanism by which cells distinguish between sustained and transient calcium signals. The subcellular localization of NFATC plays a key role in the regulation of gene transcription. Tissue Specificity: Expressed in |
Other Names | [Nuclear factor of activated T-cells; cytoplasmic 2; NF-ATc2; NFATc2; NFAT pre-existing subunit; NF-ATp; T-cell transcription factor NFAT1; NFATC2; NFAT1; NFATP], [NFATC2] |
Gene, Accession # | [NFAT1], Gene ID: 4773, NCBI: NP_001129493.1, UniProt: Q13469 |
Catalog # | MBS179508 |
Price | $160, $340, $340 |
Order / More Info | NFAT1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |