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Antigenic Specificity | alpha smooth muscle Actin |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: alpha smooth muscle Actin Antibody detects endogenous levels of total alpha smooth muscle Actin. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. Defects in ACTA2 are the cause of aortic aneurysm familial thoracic type 6 (AAT6) [MIM:611788]. They are primarily associated with a characteristic histologic appearance known as ' medial necrosis' or ' Erdheim cystic medial necrosis' in which there is degeneration and fragmentation of elastic fibers, loss of smooth muscle cells, and an accumulation of basophilic ground substance. |
Immunogen | Immunogen: A synthesized peptide derived from human alpha smooth muscle Actin |
Other Names | [Actin; aortic smooth muscle; Alpha-actin-2; Cell growth-inhibiting gene 46 protein; ACTA2; ACTSA; ACTVS; GIG46], [ACTA2; ACTA2; ACTSA; ACTSA; ACTVS] |
Gene, Accession # | Gene ID: 59, NCBI: NP_001135417.1, UniProt: P62736 |
Catalog # | MBS477723 |
Price | $335 |
Order / More Info | alpha smooth muscle Actin Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |