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Antigenic Specificity | USP51 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: USP51 antibody detects endogenous levels of total USP51. Function: Specifically deubiquitinates 'Lys-14' (H2AK13Ub) and 'Lys-16'(H2AK15Ub) of histone H2A regulating the DNA damage response at double-strand breaks (DSBs) (PubMed:27083998). USP51 is recruited to chromatin after DNA damage and regulates the dynamic assembly/disassembly of TP53BP1 and BRCA1. Exhibits also activity for 'Lys-27' or 'Lys-63'-linked di-ubiquitin (PubMed:27083998).Subunit Structure: Interacts with H2A (PubMed:27083998).Similarity: Belongs to the peptidase C19 family. |
Immunogen | Immunogen: A synthesized peptide derived from human USP51 Tissue Specificity: Expressed in prostate, brain, lung, aorta and kidney. Predicted Cross Reactivity: Pig, Horse, Rabbit Similarity: Pig (80%), Horse (100%), Rabbit (80%) |
Other Names | [Deubiquitinating enzyme 51; Ubiquitin carboxyl-terminal hydrolase 51; Ubiquitin specific peptidase 51; Ubiquitin thioesterase 51; Ubiquitin thiolesterase 51; Ubiquitin-specific-processing protease 51; UBP51_HUMAN; USP51] |
Gene, Accession # | [USP51], Gene ID: 158880, NCBI: NP_958443.1, UniProt: Q70EK9 |
Catalog # | MBS9610308 |
Price | $240, $280 |
Order / More Info | USP51 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |