USP51 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityUSP51
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionSpecificity: USP51 antibody detects endogenous levels of total USP51. Function: Specifically deubiquitinates 'Lys-14' (H2AK13Ub) and 'Lys-16'(H2AK15Ub) of histone H2A regulating the DNA damage response at double-strand breaks (DSBs) (PubMed:27083998). USP51 is recruited to chromatin after DNA damage and regulates the dynamic assembly/disassembly of TP53BP1 and BRCA1. Exhibits also activity for 'Lys-27' or 'Lys-63'-linked di-ubiquitin (PubMed:27083998).Subunit Structure: Interacts with H2A (PubMed:27083998).Similarity: Belongs to the peptidase C19 family.
ImmunogenImmunogen: A synthesized peptide derived from human USP51 Tissue Specificity: Expressed in prostate, brain, lung, aorta and kidney. Predicted Cross Reactivity: Pig, Horse, Rabbit Similarity: Pig (80%), Horse (100%), Rabbit (80%)
Other Names[Deubiquitinating enzyme 51; Ubiquitin carboxyl-terminal hydrolase 51; Ubiquitin specific peptidase 51; Ubiquitin thioesterase 51; Ubiquitin thiolesterase 51; Ubiquitin-specific-processing protease 51; UBP51_HUMAN; USP51]
Gene, Accession #[USP51], Gene ID: 158880, NCBI: NP_958443.1, UniProt: Q70EK9
Catalog #MBS9610308
Price$240, $280
Order / More InfoUSP51 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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