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Antigenic Specificity | IRF4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.02 mL, 0.06 mL, 0.12 mL |
Concentration | 2.8mg/mL |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The protein encoded by this gene belongs to the IRF (interferon regulatory factor) family of transcription factors, characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. This family member is lymphocyte specific and negatively regulates Toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(6; 14)(p25; q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found for this gene. |
Immunogen | Immunogen: Synthetic peptide of human IRF4 Calculated Molecular Weight: 52kDa |
Other Names | [MUM1; LSIRF; NF-EM5] |
Gene, Accession # | [IRF4], Gene ID: 3662, NCBI: NP_001182215.1 |
Catalog # | MBS2522424 |
Price | $110, $150, $225 |
Order / More Info | IRF4 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |