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Antigenic Specificity | Caspase-9 (I16) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | n/a |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | Immunoblot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Anti-Caspase-9 (116) [Rabbit antibody to peptide corresponding to aa 41-56 of human caspase-9.]. This antibody recognizes full-length human caspase-9 (46 kD). Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain-containing adapter molecules and members of the caspase family of proteases. Caspase-9 and Apaf-1 bind to each other, which leads to caspase-9 activation. Caspase-9 is also activated by granzyme B and CPP32. Activated caspase-9 cleaves and activates caspase-3, a protease responsible for proteolytic cleavage of many key proteins involved in apoptosis. Caspase-9 plays a central role in cell death induced by a wide variety |
Immunogen | Antigen: Peptide corresponding to aa 41-56 of human caspase-9. |
Other Names | [Caspase-9 (116); Caspase-9 (I16)], [CASP9; CASP9; MCH6; APAF3; APAF-3; ICE-LAP6; CASPASE-9c; MCH6] |
Gene, Accession # | Gene ID: 842, NCBI: BAA87905.1, UniProt: P55211 |
Catalog # | MBS194392 |
Price | $415 |
Order / More Info | Caspase-9 (I16) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |