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Antigenic Specificity | RGS9 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: RGS9 antibody detects endogenous levels of total RGS9. Function: Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to GNAT1. Involved in phototransduction; key element in the recovery phase of visual transduction (By similarity).Subunit Structure: Heterodimer with GNB5. Interacts with RGS7BP, leading to regulate the subcellular location of the heterodimer formed with GNB5. Component of the RGS9-1-Gbeta5 complex composed of RGS9 (RGS9-1), Gbeta5 (GNB5) and RGS9BP. Interacts with PDE6G and GNAT1.Post-translational Modifications: Retinal isoform 3 is light-dependent phosphorylated at 'Ser-478'. Phosphorylation is decreas |
Immunogen | Immunogen: A synthesized peptide derived from human RGS9 Subcellular Location: Membrane. Isoform 3 is targeted to the membrane via its interaction with RGS9BP. Tissue Specificity: Highly expressed in the caudate and putamen, lower levels found in the hypothalamus and nucleus accumbens and very low levels in cerebellum. Not expressed in globus pallidus or cingulate cortex. Isoform 2 is expressed predominantly in pineal gland and retina. Isoform 3 is expressed in retina (abundant in photoreceptors |
Other Names | [PERRS; R9AP; Regulator of G protein signalling 9; Regulator of G-protein signaling 9; RGS9; RGS9_HUMAN; RGS9L] |
Gene, Accession # | [RGS9], Gene ID: 8787, NCBI: NP_001075424.1, UniProt: O75916 |
Catalog # | MBS9608476 |
Price | $240, $280 |
Order / More Info | RGS9 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |