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Antigenic Specificity | CD25 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | epitope affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Flow Cytometry (FC/FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody reacts with human. The other species are not tested. The IL2 receptor (IL2R) exists in three alternative forms made up from the individual components of CD25, CD122, and CD132. CD25 represents the low affinity alpha chain of the IL2R, a type I transmembrane glycoprotein containing two CCP domains. It is rich in O linked carbohydrates and has a short cytoplasmic tail. CD25 is expressed on activated T cells, B cells, NK cells and monocytes of all mouse strains tested. It is transiently expressed at a low level during B cell development in bone marrow on the CD45R/B220 low TdT- sIg- pre-B II and CD45R/B220low TdT- sIgM+sIgD- immature B cells, but not on the CD45R/B220 low TdT+ sIg- pro-B/pre B I stage nor on CD45R/B220high TdT- s |
Immunogen | n/a |
Other Names | [IL2RA; Interleukin2 receptor alpha], [IL2RA; Pmp22; p55; CD25; IL2R; IMD41; TCGFR; IDDM10; Cd25; Pmp-22; PMP-22; SAG] |
Gene, Accession # | [CD25], Gene ID: 3559, NCBI: CAA44297.1, UniProt: P25094 |
Catalog # | MBS460103 |
Price | $285 |
Order / More Info | CD25 Antibody from MYBIOSOURCE INC. |
Product Specific References | Amu, S. and Brisslert, M. Phenotype and function of CD25-expressing B lymphocytes isolated from human umbilical cord blood. Clin. Dev. Immunol. 2011, 481948 (2011). |