MLK1 (C-term), 1070-1104 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityMLK1 (C-term), 1070-1104
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpurified
Size0.08 mL, 0.4 mL
Concentrationvial concentration: 2
ApplicationsWestern Blot (WB), ELISA (EIA), Immunohistochemistry (IHC)
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DescriptionThis MLK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1070-1104 amino acids from the C-terminal region of human MLK1. MLK1 is a MLK(MAP3K) type protein kinase. The catalytic domain of mixed-lineage kinases (MLKs) kinases have amino acid sequence similarity to both the tyr-specific and the ser/thr-specific kinase classes. In addition to thee unusual nature of the kinase catalytic domains, MLK1 and MLK2 contain 2 leu/ile-zipper motifs and a basic sequence near their C-termini. MLK1 is a member of the neuronal apoptotic JNK/c-Jun pathway acting between Rac1/Cdc42 and MKK4 and -7 in death signaling. MLK1 expression has been documented in human epithelial tumor cell lines of colonic, breast and es
Immunogenn/a
Other Names[Mitogen-activated protein kinase kinase kinase 9; Mixed lineage kinase 1; MAP3K9; MLK1; PRKE1]
Gene, Accession #[MAP3K9], Gene ID: 4293, NCBI: NP_149132.2, UniProt: P80192
Catalog #MBS9214102
Price$165, $370
Order / More InfoMLK1 (C-term), 1070-1104 Antibody from MYBIOSOURCE INC.
Product Specific ReferencesDurkin, J.T., et al., Biochemistry 43(51):16348-16355 (2004). Gallo, K.A., et al., J. Biol. Chem. 269(21):15092-15100 (1994). Dorow, D.S., et al., Eur. J. Biochem. 213(2):701-710 (1993).
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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