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Antigenic Specificity | TUBB4B |
Clone | [7D2] |
Host Species | Mouse |
Reactive Species | human |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain.Some glutamate residues at the C-terminus are polyglutamylated. This modification occurs exclusively on glutamate residues and results in polyglutamate chains on the gamma-carboxyl group. Also monoglycylated but not polyglycylated due to the absence of functional TTLL10 in human. Monoglycylation is mainly limited to tubulin incorporated into axonemes (cilia and flagella) whereas glutamylation is prevalent in neuronal cells, centrioles, axonemes, and the mitotic spindle. Both modifications can coexist on the same protein on adjacent residues, and lowering glycylation |
Immunogen | n/a |
Other Names | [tubulin beta-4B chain; Tubulin beta-4B chain; tubulin beta-4B chain; tubulin beta 4B class IVb; Tubulin beta-2 chain; Tubulin beta-2C chain] |
Gene, Accession # | [TUBB4B], Gene ID: 10383, NCBI: NP_006079, UniProt: P68371 |
Catalog # | MBS3200077 |
Price | $290 |
Order / More Info | TUBB4B Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |