TUBB4B Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityTUBB4B
Clone[7D2]
Host SpeciesMouse
Reactive Specieshuman
Isotypen/a
Formatunconjugated
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionTubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain.Some glutamate residues at the C-terminus are polyglutamylated. This modification occurs exclusively on glutamate residues and results in polyglutamate chains on the gamma-carboxyl group. Also monoglycylated but not polyglycylated due to the absence of functional TTLL10 in human. Monoglycylation is mainly limited to tubulin incorporated into axonemes (cilia and flagella) whereas glutamylation is prevalent in neuronal cells, centrioles, axonemes, and the mitotic spindle. Both modifications can coexist on the same protein on adjacent residues, and lowering glycylation
Immunogenn/a
Other Names[tubulin beta-4B chain; Tubulin beta-4B chain; tubulin beta-4B chain; tubulin beta 4B class IVb; Tubulin beta-2 chain; Tubulin beta-2C chain]
Gene, Accession #[TUBB4B], Gene ID: 10383, NCBI: NP_006079, UniProt: P68371
Catalog #MBS3200077
Price$290
Order / More InfoTUBB4B Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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