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Antigenic Specificity | BMP4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous level of total BMP4 antibody. Bone morphogenetic proteins (BMPs) were first identified as molecules that can induce ectopic bone and cartilage formation (1,2). BMPs belongs to the TGF-b superfamily, playing many diverse functions during development (3). BMPs are synthesized as precursor proteins and then processed by cleavage to release the c-terminal mature BMP. BMPs initiate signaling by binding to a receptor complex containing type I and type II serine/threonine receptor kinases that then phosphorylate Smad (mainly Smad1, 5 and 8), resulting the translocation of Smad into the nucleus. BMP was also reported to activate MAPK pathways in some systems (3,4). BMP4 plays an essential role during development. Mou |
Immunogen | Immunogen Type: Recombinant Protein Immunogen Description: Recombinant protein of human BMP4. |
Other Names | [BMP2B; BMP2B1; MCOPS6; ZYME] |
Gene, Accession # | [BMP4], Gene ID: 652, NCBI: NP_001193.2, UniProt: P12644 |
Catalog # | MBS9401115 |
Price | $255 |
Order / More Info | BMP4 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |