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Antigenic Specificity | LARP7 (C-term), 527-556 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human (predicted reactivity: monkey, mouse, rat) |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.44 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This LARP7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 527-556 amino acids from the C-terminal region of human LARP7. LARP7 is a negative transcriptional regulator of polymerase II genes, acting by means of the 7SK RNP system. Within the 7SK RNP complex, the positive transcription elongation factor b (P-TEFb) is sequestered in an inactive form, preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation. |
Immunogen | n/a |
Other Names | [La-related protein 7; La ribonucleoprotein domain family member 7; P-TEFb-interaction protein for 7SK stability; PIP7S; LARP7] |
Gene, Accession # | [LARP7], Gene ID: 51574, NCBI: NP_001253968.1, UniProt: Q4G0J3 |
Catalog # | MBS9204064 |
Price | $165, $370 |
Order / More Info | LARP7 (C-term), 527-556 Antibody from MYBIOSOURCE INC. |
Product Specific References | Tyagi, M., et al. J. Virol. 84(13):6425-6437(2010) Kalsi, G., et al. Hum. Mol. Genet. 19(12):2497-2506(2010) Markert, A., et al. EMBO Rep. 9(6):569-575(2008) Krueger, B.J., et al. Nucleic Acids Res. 36(7):2219-2229(2008) He, N., et al. Mol. Cell 29(5):588-599(2008) |