Edit |   |
---|---|
Antigenic Specificity | Mouse IL-28B |
Clone | [23A14] |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgG2 |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Neutr |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Human/mouse IL-28A (IFN-lambda 2), IL-28B (IFN-lambda 3), and human IL-29 (IFN-lambda 1) are class II cytokine receptor ligands that are distantly related to members of the IL-10 family (11 - 13% amino acid (aa) sequence identity) and type I IFN family (15 - 19% aa sequence identity). These cytokines exert bioactivities that overlap those of type I IFNs, including antiviral activity and up-regulation of MHC class I antigen expression. The proteins signal through the same heterodimeric receptor complex that is composed of the IL-10 receptor beta (IL-10 R beta) and a novel IL-28 receptor alpha (IL-28 R alpha, also known as IFN-lambda R1). Mouse IL-28 shares 61%, 62%, and 52% aa identity with human IL-28A, IL-28B, and IL-29, respectively. |
Immunogen | Antibody Generation: This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a rat) immunized with mouse recombinant protein of IL-28B. |
Other Names | [Il28b; Il28; IFL-1; IL-28B; INF-alpha; INF-lambda], [Ifnl3; Ifnl3; Il28; IFL-1; Il28b; IL-28B; INF-alpha; INF-lambda; Il28; Il28b; IFN-lambda-3; IL-28B] |
Gene, Accession # | [IL-28B], Gene ID: 338374, NCBI: NP_796370.1, UniProt: Q8CGK6 |
Catalog # | MBS690914 |
Price | $490 |
Order / More Info | Mouse IL-28B Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |