Phospho-Tyr1472 NMDA NR2B-Subunit Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Phospho-Tyr1472 NMDA NR2B-Subunit |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Specific for the ~180k NMDAR NR2B-subunit protein phosphorylated at Tyr1472 in Western blots. The antibody also labels proteins of ~65k and ~115k. Immunolabeling is completely blocked by blocked by either lambda-Ptase or by the phosphopeptide used as the antigen but not by the corresponding dephosphopeptide. Affinity purified rabbit polyclonal antibody |
| Immunogen | Antigen: Phosphopeptide corresponding to amino acid residues surrounding the phospho-Tyr1472 of NMDA NR2B. Immunogen Information: Synthetic phospho-peptide corresponding to amino acid residues surrounding Tyr1472 conjugated to KLH. Immunogen Species: Rat |
| Other Names | [glutamate receptor ionotropic, NMDA 2B; Glutamate receptor ionotropic, NMDA 2B; glutamate receptor ionotropic, NMDA 2B; NR2B; NMDAR2B; glutamate receptor, ionotropic, NMDA2B; N-methyl D-aspartate receptor subtype 2B; glutamate [NMDA] receptor subunit epsilon-2; glutamate receptor, ionotropic, N-methyl D-aspartate 2B; Glutamate [NMDA] receptor subunit epsilon-2; N-methyl D-aspartate receptor subtype 2B], [Grin2b; Grin2b; GluN2B; GluN2B; NMDAR2B; NR2B] |
| Gene, Accession # | [GRIN2B], Gene ID: 24410, NCBI: NP_036706.1, UniProt: Q00960 |
| Catalog # | MBS502091 |
| Price | $360 |
| Order / More Info | Phospho-Tyr1472 NMDA NR2B-Subunit Antibody from MYBIOSOURCE INC. |
| Product Specific References | • Alvestad RM, Grosshans DR, Coultrap SJ, Nakazawa T, Yamamoto T, Browning MD (2003) Tyrosine dephosphorylation and ethanol inhibition of N-methyl-D-aspartate receptor function. J Biol Chem 278:11020-11025.• Carroll RC, Zukin RS (2002) NMDA-receptor trafficking and targeting: implications for synaptic transmission and plasticity. Trends Neurosci 25:571-577.• Clayton DA, Grosshans DR, Browning MD (2002a) Aging and surface expression of hippocampal NMDA receptors. J Biol Chem 277:14367-14369.• Clayton DA, Mesches MH, Alvarez E, Bickford PC, Browning MD (2002b) A hippocampal NR2B deficit can mimic age-related changes in long-term potentiation and spatial learning in the Fischer 344 rat. J Neurosci 22:3628-3637.• Grosshans DR, Clayton DA, Coultrap SJ, Browning MD (2002) LTP leads to rapid surface expression of NMDA but not AMPA receptors in adult rat CA1. Nat Neurosci 5:27-33. |
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MYBIOSOURCE INC.
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