Edit |   |
---|---|
Antigenic Specificity | Human CASP9 / Caspase 9 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 0.05 mg |
Concentration | 1 mg/ml |
Applications | Immunohistochemistry (IHC - Paraffin), Immunocytochemistry (ICC), Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: peptide corresponding to amino acids 299 to 318 of human caspase-9. Caspase 9 is a cysteine C14 endopeptidase that mediates oncogene and drug-induced apoptosis. It is activated upon binding to Apaf-1/cytochrome c and inhibited upon phosphorylation by the serine/ threonine kinase Akt. Activated caspase-9 cleaves downstream caspases such as Caspase-3, -6 and -7 initiating the caspase cascade. Like other caspases, Caspase-9 plays a critical role in mediating apoptosis during normal brain development. |
Immunogen | Immunogen Description: Synthetic peptide from human CASP9 / Caspase 9. |
Other Names | [CASP9 / Caspase 9 (aa299-318) IHC-plus; CASP9; APAF3; CASPASE-9c; ICE-LAP6; MCH6; ICE-like apoptotic protease 6; APAF-3; Apoptotic protease Mch-6; CASP-9; Caspase 9; Caspase-9; PPP1R56; Human CASP9; Caspase 9], [CASP9; CASP9; MCH6; APAF3; APAF-3; PPP1R56; ICE-LAP6; MCH6; CASP-9; APAF-3; ICE-LAP6] |
Gene, Accession # | [CASP9], Gene ID: 842, NCBI: NP_001220.2, UniProt: P55211 |
Catalog # | MBS244551 |
Price | $530 |
Order / More Info | Human CASP9 / Caspase 9 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |