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Antigenic Specificity | PIK3R4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: PIK3R4 antibody detects endogenous levels of total PIK3R4. Function: Regulatory subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate; different complex forms are believed to play a role in multiple membrane trafficking pathways: PI3KC3-C1 is involved in initiation of autophagosomes and PI3KC3-C2 in maturation of autophagosomes and endocytosis. Involved in regulation of degradative endocytic trafficking and cytokinesis, probably in the context of PI3KC3-C2 (PubMed:20643123).Subunit Structure: Component of the PI3K (PI3KC3/PI3K-III/class III phosphatidylinositol 3-kinase) complex the core of which is composed of the catalytic subunit PIK3C3, the regulatory subunit PIK3R4 and BECN1 associatin |
Immunogen | Immunogen: A synthesized peptide derived from human PIK3R4 Subcellular Location: Endosome Tissue Specificity: Ubiquitously expressed. Predicted Cross Reactivity: Pig, Zebrafish, Bovine, Horse, Rabbit, Dog, Xenopus Similarity: Pig (92%), Zebrafish (83%), Bovine (92%), Horse (100%), Rabbit (92%), Dog (92%), Xenopus (83%) |
Other Names | [MGC102700; P150; Phosphatidylinositol 3 kinase associated p150; Phosphatidylinositol 3 kinase regulatory subunit polypeptide 4; Phosphatidylinositol 3 kinase regulatory subunit polypeptide 4 p150; Phosphoinositide 3 kinase adaptor protein; Phosphoinositide 3 kinase regulatory subunit 4; Phosphoinositide 3 kinase regulatory subunit 4 p150; Phosphoinositide 3 kinase regulatory subunit polypeptide 4; Phosphoinositide 3 kinase regulatory subunit polypeptide 4 p150; Phosphoinositide 3-kinase adaptor protein; Phosphoinositide 3-kinase regulatory subunit 4; PI3 kinase p150 subunit; PI3-kinase p150 subunit; PI3-kinase regulatory subunit 4; PI3R4_HUMAN; PIK3R 4; PIK3R4; VPS 15; VPS15] |
Gene, Accession # | [PIK3R4], Gene ID: 30849, NCBI: NP_055417.1, UniProt: Q99570 |
Catalog # | MBS9608785 |
Price | $240, $280 |
Order / More Info | PIK3R4 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |