RIPK3 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityRIPK3
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciesbovine, human, porcine, monkey
Isotypen/a
Formataffinity purified
Size0.1 mg
Concentration0.66-0.68 ug/ul in antibody stabilization buffer
ApplicationsELISA (EIA), IMM, Western Blot (WB)
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DescriptionAffinity Purified Receptor-interacting Serine/Threonine-protein kinase 3 Antibody C-epitope. Essential for necroptosis, a programmed cell death process in response to death-inducing TNF-alpha family members. Upon induction of necrosis, RIPK3 interacts with, and phosphorylates RIPK1 and MLKL to form a necrosis-inducing complex. RIPK3 binds to and enhances the activity of three metabolic enzymes: GLUL, GLUD1, and PYGL.
ImmunogenImmunogen: Synthetic peptide taken within amino acid region 461-511 on human Receptor-interacting Serine/Threonine-protein kinase 3 protein. Expression: Highly expressed in the pancreas. Detected at lower levels in heart, placenta, lung and kidney. Isoform 3 is significantly increased in colon and lung cancers.
Other Names[Receptor interacting protein 3; Receptor interacting serine threonine kinase 3; Receptor-interacting protein 3; RIP 3; RIP like protein kinase 3; RIPK 3], [RIPK3; RIPK3; RIP3; RIP3; RIP-3]
Gene, Accession #[RIPK3], Gene ID: 11035, NCBI: NP_006862.2, UniProt: Q9Y572
Catalog #MBS540850
Price$390
Order / More InfoRIPK3 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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