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Antigenic Specificity | RIPK3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | bovine, human, porcine, monkey |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 0.66-0.68 ug/ul in antibody stabilization buffer |
Applications | ELISA (EIA), IMM, Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Affinity Purified Receptor-interacting Serine/Threonine-protein kinase 3 Antibody C-epitope. Essential for necroptosis, a programmed cell death process in response to death-inducing TNF-alpha family members. Upon induction of necrosis, RIPK3 interacts with, and phosphorylates RIPK1 and MLKL to form a necrosis-inducing complex. RIPK3 binds to and enhances the activity of three metabolic enzymes: GLUL, GLUD1, and PYGL. |
Immunogen | Immunogen: Synthetic peptide taken within amino acid region 461-511 on human Receptor-interacting Serine/Threonine-protein kinase 3 protein. Expression: Highly expressed in the pancreas. Detected at lower levels in heart, placenta, lung and kidney. Isoform 3 is significantly increased in colon and lung cancers. |
Other Names | [Receptor interacting protein 3; Receptor interacting serine threonine kinase 3; Receptor-interacting protein 3; RIP 3; RIP like protein kinase 3; RIPK 3], [RIPK3; RIPK3; RIP3; RIP3; RIP-3] |
Gene, Accession # | [RIPK3], Gene ID: 11035, NCBI: NP_006862.2, UniProt: Q9Y572 |
Catalog # | MBS540850 |
Price | $390 |
Order / More Info | RIPK3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |