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Antigenic Specificity | ZFAND5 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.02 mL, 0.06 mL, 0.12 mL |
Concentration | 1.4mg/mL |
Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Involved in protein degradation via the ubiquitin-proteasome system. May act by anchoring ubiquitinated proteins to the proteasome. Plays a role in ubiquitin-mediated protein degradation during muscle atrophy. Plays a role in the regulation of NF-kappa-B activation and apoptosis. Inhibits NF-kappa-B activation triggered by overexpression of RIPK1 and TRAF6 but not of RELA. Inhibits also tumor necrosis factor (TNF), IL-1 and TLR4-induced NF-kappa-B activation in a dose-dependent manner. Overexpression sensitizes cells to TNF-induced apoptosis. Is a potent inhibitory factor for osteoclast differentiation. |
Immunogen | Immunogen: Full length fusion protein |
Other Names | [AN1-type zinc finger protein 5; ZA20D2; ZFAN5; Zfand5; ZFAND5A; Zinc finger A20 domain containing 2; Zinc finger A20 domain containing protein 2; Zinc finger A20 domain-containing protein 2; Zinc finger AN1 type domain 5; Zinc finger protein 216; ZNF216] |
Gene, Accession # | [ZFAND5], Gene ID: 7763, NCBI: NP_001095890.1, UniProt: O76080 |
Catalog # | MBS2560210 |
Price | $110, $150, $225 |
Order / More Info | ZFAND5 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |