Edit |   |
---|---|
Antigenic Specificity | TAL-1 (Phospho-Ser122) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | epitope affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of TAL-1 only when phosphorylated at serine 122. TAL-1 is a basic helix-loop-helix transcription. Regulates differentiation and survival during hemopoiesis. Implicated in the genesis of hemopoietic malignancies. It may play an important role in hemopoietic differentiation. Serves as a positive regulator of eryhtroid differentiation. Mutations are associated with T-cell leukemia and melanoma. Binds to the LIM domain containing protein Rhombotin-2. Aplan P.D., Mol. Cell. Biol. 10:6426-6435(1990).Gregory S.G., Nature 441:315-321(2006).Chen Q., J. Exp. Med. 172:1403-1408(1990). |
Immunogen | Immunogen Type: Peptide-KLH Immunogen Description: Peptide sequence around phosphorylation site of Serine 122(Q-L-S(p)-P-P) derived from Human TAL-1. |
Other Names | [SCL; TAL1; TCL5] |
Gene, Accession # | [TAL-1], Gene ID: 6886, NCBI: NP_001274276.1, UniProt: P17542 |
Catalog # | MBS9402398 |
Price | $200, $255 |
Order / More Info | TAL-1 (Phospho-Ser122) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |