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Antigenic Specificity | JADE1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Transcriptional coactivator, it may also promote acetylation of nucleosomal histone H4 by KAT5. Promotes apoptosis. May act as a renal tumor suppressor. Negatively regulates canonical Wnt signaling; at least in part, cooperates with NPHP4 in this function. |
Immunogen | Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 210-509 of human JADE1 (NP 079176.2). |
Other Names | [PHF17] |
Gene, Accession # | [JADE1], Gene ID: 79960, NCBI: NP_079176, UniProt: Q6IE81 |
Catalog # | MBS8548334 |
Price | $280 |
Order / More Info | JADE1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |